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Amphotericin B CAS 1397-89-3

Chemical name:Amphotericin B

Synonymous names:Fungilin;

Fungizone

CAS No:1397-89-3

Molecular formula: C47H73NO17

Purity: 99.0%

Appearance:Yellow or orange-yellow powder

Molecular weight:924.08

EINECS:215-742-2

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Structural formula 

Amphotericin B CAS 1397-89-3 supplier 

Product Description

 Items

Index

Description

Yellow to orange powder; odorless or practically so.       

Solubility

Soluble in dimethyl sulfoxide; insoluble in water, in anhydrous alcohol, in ether, in benzene, and in toluene.

Identification

UV: conform to the requirement of USP Amphotericin B monograph

Loss on Drying,%

5.0MAX

Residue on ignition  , %           

3.0MAX               

Assay(microbial)                         

≥750 μg of C4H73NO17 per mg, calculated on the dried basis.     

Amphotericin A,%

15.0MAX

Residual Solvents

Methanol

3000MAX ppm

 

Acetone

5000MAX ppm

 

Properties and Usage:

Amphotericin B is a polyene antifungal drug that is widely used to treat a variety of fungal infections. Its powerful inhibitory or killing effect covers effective control of new fungi.

1. Strong inhibitory effect: Amphotericin B combines with sterols on the fungal cell membrane, damaging the permeability of the membrane, causing potassium ions, nucleotides, amino acids, etc. in the bacterial cells to leak out, thereby destroying the normal metabolism of the fungus. Play an inhibitory role.

The main purpose:

2. Treatment of deep mycosis: Amphotericin B is the drug of choice for deep mycosis, especially suitable for the treatment of severe visceral or systemic infections caused by deep fungi.

in conclusion:

Storage conditions: This product should be stored tightly sealed in a cool, dry warehouse.

Packing: 1kg aluminum foil bagOr 1kg per aluminum can package also be customized according to customer's requirements

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