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Triethyl orthoformate CAS 122-51-0

Chemical name: Triethyl orthoformate

Synonymous names:Triethyl Orthopropionate;Methane, triethoxy-;Ethyl Orthopropionate

CAS No:122-51-0

Molecular formula:C7H16O3

Molecular weight:148.2

EINECS No:204-550-4

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Structural formula  

Product Description

Items

Specifications

Appearance

Colorless liquid

Melting point

-76 °C (lit.)

Boiling point

146 °C (lit.)

Density

0.891 g/mL at 25 °C (lit.)

Vapor density

5.11 (vs air)

 

Properties and Usage:

Triethyl orthoformate (CAS 122-51-0), referred to as TEOF, is a colorless, transparent liquid with a slight aromatic odor. It is used in medicine, pesticides, coatings and other fields.

 

1. Pharmaceutical industry: Participating in drug synthesis

Triethyl orthoformate is not only used in the production of sulfonamides, cephalosporins and anti-tumor drugs, but also in the production of antimalarial drugs chloroquine and quinazoline.

 

2. Pesticide synthesis: Providing excellent reactivity and high-efficiency pesticides

Triethyl orthoformate is used in the production of pesticides to synthesize high-efficiency insecticides and fungicides with nitrogen heterocyclic structures. It is a key intermediate of amitraz (acaricide) and pyrazosulfuron-methyl (herbicide) with good reactivity.

 

3. Coatings and resins industry: Improving adhesion and durability

As a coating additive and resin modifier, it improves the adhesion, durability and gloss of coatings. It can also enhance the chemical properties of products in the synthesis of special resins and enhance the market competitiveness of coatings and resins.

 

4. Organic synthesis intermediates: methylation and catalysis

Triethyl orthoformate is used as a methylation agent in organic synthesis and participates in the preparation of alcohols, aldehydes and ester compounds. In addition, it also plays the role of catalyst or raw material in condensation reactions, nitration and amination reactions.

 

5. Flavors and fine chemicals: giving unique aromas and characteristics

Triethyl orthoformate is often used to give products unique aromas or other chemical characteristics in the production of flavors and fine chemicals because it is easy to participate in esterification and other chemical reactions.

 

Storage conditions: Storage precautions Store in a cool, ventilated warehouse. Keep away from fire and heat sources. The warehouse temperature should not exceed 37°C. Keep the container sealed. Store separately from oxidants, acids, etc. and avoid mixed storage. Use explosion-proof lighting and ventilation facilities. Do not use mechanical equipment and tools that are prone to sparks. The storage area should be equipped with leakage emergency treatment equipment and appropriate containment materials.

Packing: This product is packed in 25kg drums, and it can also be customized according to customers' requirements

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