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Potassium tert-butoxide CAS 865-47-4

Chemical name: Potassium tert-butoxide

Synonymous names:BuOk(PotassiuM tert-butoxide);PotassiuM tert-butoxide solution 1.0 M in THF;PotassiuM tert-butyl alcohol

CAS No:865-47-4

Molecular formula:C4H9KO

Molecular weight:112.21

EINECS No:212-740-3

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Structural formula  

Product Description

Items

Index

Appearance

white or almost white hygroscopic powder

Melting point

256-258 ℃ (dec.)(lit.)

Boiling point

275℃

Vapor pressure

1 mm Hg (220 ℃)

 

Properties and Usage:

Potassium tert-butoxide (CAS 865-47-4) is an organic potassium compound with strong alkalinity, which is used in organic synthesis and chemical reactions, especially in the preparation of high-purity chemicals and reactions as catalysts.

 

1. Catalytic effect in organic synthesis

As a strong base catalyst, potassium tert-butoxide participates in nucleophilic substitution, elimination and dehydrogenation reactions, promotes the formation or breakage of carbon-carbon bonds, and is used in the preparation of chemical intermediates.

 

2. Dehydrogenation reaction of alcohol compounds

Under certain conditions, potassium tert-butoxide can promote the dehydrogenation reaction of alcohols to generate olefins or aromatic compounds, and is often used in the synthesis of olefins and important chemicals.

 

3. Formation of carbon-carbon bonds

Potassium tert-butoxide can be used as a strong base in Wittig reaction and Aldol reaction to promote the formation of carbon-carbon bonds, generate negative ion intermediates, and react with other substances to form new carbon-carbon bonds.

 

4. Deprotonation reaction

As a deprotonating agent, potassium tert-butoxide can remove hydrogen ions from organic molecules, generate alkaline organic anions, and promote nucleophilic substitution and elimination reactions.

 

5. Application in olefin synthesis

Potassium tert-butoxide helps convert saturated hydrocarbons into olefins in dehydrogenation reactions, and is particularly suitable for the synthesis of long-chain olefins.

 

6. Reactants in liquid phase reactions

In liquid phase organic reactions, potassium tert-butoxide, as a solvent and a ligand of reactants, can increase the reaction rate and selectivity and optimize the reaction effect.

 

7. Role in drug synthesis

As a strong base, potassium tert-butoxide participates in deprotonation reactions in drug synthesis, helps generate active intermediates, and promotes the synthesis of drug molecules.

 

8. Reducing agent and reaction medium

Potassium tert-butoxide acts as a reducing agent in certain chemical reactions, promotes reduction and elimination in organic chemical reactions, and helps functional group transformation.

 

Storage conditions: Store under dry inert gas, keep the container tightly sealed, in a cool, dry place

Packing: This product is packed in 25kg cardboard drums, and it can also be customized according to customers' requirements

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