Potassium tert-butoxide CAS 865-47-4
Chemical name: Potassium tert-butoxide
Synonymous names:BuOk(PotassiuM tert-butoxide);PotassiuM tert-butoxide solution 1.0 M in THF;PotassiuM tert-butyl alcohol
CAS No:865-47-4
Molecular formula:C4H9KO
Molecular weight:112.21
EINECS No:212-740-3
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Structural formula:
Product Description:
Items |
Index |
Appearance |
white or almost white hygroscopic powder |
Melting point |
256-258 ℃ (dec.)(lit.) |
Boiling point |
275℃ |
Vapor pressure |
1 mm Hg (220 ℃) |
Properties and Usage:
Potassium tert-butoxide (CAS 865-47-4) is an organic potassium compound with strong alkalinity, which is used in organic synthesis and chemical reactions, especially in the preparation of high-purity chemicals and reactions as catalysts.
1. Catalytic effect in organic synthesis
As a strong base catalyst, potassium tert-butoxide participates in nucleophilic substitution, elimination and dehydrogenation reactions, promotes the formation or breakage of carbon-carbon bonds, and is used in the preparation of chemical intermediates.
2. Dehydrogenation reaction of alcohol compounds
Under certain conditions, potassium tert-butoxide can promote the dehydrogenation reaction of alcohols to generate olefins or aromatic compounds, and is often used in the synthesis of olefins and important chemicals.
3. Formation of carbon-carbon bonds
Potassium tert-butoxide can be used as a strong base in Wittig reaction and Aldol reaction to promote the formation of carbon-carbon bonds, generate negative ion intermediates, and react with other substances to form new carbon-carbon bonds.
4. Deprotonation reaction
As a deprotonating agent, potassium tert-butoxide can remove hydrogen ions from organic molecules, generate alkaline organic anions, and promote nucleophilic substitution and elimination reactions.
5. Application in olefin synthesis
Potassium tert-butoxide helps convert saturated hydrocarbons into olefins in dehydrogenation reactions, and is particularly suitable for the synthesis of long-chain olefins.
6. Reactants in liquid phase reactions
In liquid phase organic reactions, potassium tert-butoxide, as a solvent and a ligand of reactants, can increase the reaction rate and selectivity and optimize the reaction effect.
7. Role in drug synthesis
As a strong base, potassium tert-butoxide participates in deprotonation reactions in drug synthesis, helps generate active intermediates, and promotes the synthesis of drug molecules.
8. Reducing agent and reaction medium
Potassium tert-butoxide acts as a reducing agent in certain chemical reactions, promotes reduction and elimination in organic chemical reactions, and helps functional group transformation.
Storage conditions: Store under dry inert gas, keep the container tightly sealed, in a cool, dry place
Packing: This product is packed in 25kg cardboard drums, and it can also be customized according to customers' requirements