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Phenylmethylsulfonyl fluoride CAS 329-98-6 PMSF

Chemical name: Phenylmethylsulfonyl fluoride

Synonymous names

Phenylmethylsulfonyl fluoride;

PMSF; 

329-98-6;

phenylmethanesulfonyl fluoride;

Benzenemethanesulfonyl fluoride;

Benzylsulfonyl fluoride

CAS No: 329-98-6

EINECS No: 206-350-2

Molecular formula: C7H7FO2S

Content: 99%

Molecular Weight: 174.19

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Structural formula:Phenylmethylsulfonyl

Product Description

Phenylmethylsulfonyl fluoride is a highly effective protease inhibitor widely used in biochemistry and molecular biology research. Its unique chemical properties make it excellent in inhibiting serine and cysteine ​​proteases, helping to prevent hydrolysis and degradation of proteins during purification, thereby maintaining protein activity and function.

ANALYSIS    TEST

STANDARD

Appearance

White to faint yellow powder or peedle like crystals

Purity(GC)

Colorless to faint yellow

Solubility (Turbidity)

Clear to very slightly hazy

Turbidity

≤4.ONTU

Melting Point

92 ° ℃~ 95 ° ℃

FT-IR Spectrum

Corresponds to reference spectrum

Uv absorbance /600nm ( 10% methanol solution)

<0.01

 

Main uses

1.Serine and cysteine ​​protease inhibitors:

Phenylmethylsulfonyl fluoride can effectively inhibit serine proteases (such as trypsin and chymotrypsin) and cysteine ​​proteases. This property makes it a commonly used protease inhibitor in research, helping to prevent protein degradation during experiments.

 

2.Enzyme inhibitors:

As a highly effective enzyme inhibitor, Phenylmethylsulfonyl fluoride can bind to enzymes, preventing the binding of normal substrates to enzymes and their catalytic reactions. This inhibitory effect is particularly important when studying the function and mechanism of enzymes.

 

3.Protease inhibitors:

Phenylmethylsulfonyl fluoride can inhibit or antagonize the biosynthesis or action of proteases (endopeptidases) and is widely used in various experiments and research projects that require controlled protein degradation.

 

Packaging specifications: 1. Store in a ventilated and dry place, pay attention to prevent rain and flooding.

2. Packed in aluminum foil bag. Store in a cool and ventilated warehouse. Keep away from fire and heat sources. Avoid direct sunlight. Packing sealed. It should be stored separately from oxidizers and alkalis and should not be mixed. Equipped with appropriate variety and quantity of fire fighting equipment. The storage area should be equipped with suitable materials to cover leakage

 

Effective concentration: 0.1-1mM

COA, TDS, and MSDS, please contact [email protected]

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