N-Bromosuccinimide (NBS) CAS 128-08-5
Chemical name: N-Bromosuccinimide
Synonymous names:NBS;bromosuccinimide;N-BROMOBUTANIMIDE
CAS No:128-08-5
Molecular formula:C4H4BrNO2
Molecular weight:177.98
EINECS No:204-877-2
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Structural formula:
Product Description:
Items |
Specifications |
Appearance |
White or light yellow crystal |
Assay |
99% MIN |
effective bromide |
44% MIN |
Water dissolution test |
water-soluble |
Acetic acid dissolution test |
meet the requirements |
chloride |
1.0% MAX |
dry weight loss |
0.5% MAX |
Properties and Usage:
N-bromosuccinimide (NBS for short) is an efficient organic chemical reagent, commonly used in bromination and oxidation reactions, with excellent selectivity and reactivity, mainly used in organic synthesis, pharmaceutical chemistry and the manufacture of polymer materials.
1. Oxidation reaction in organic synthesis
NBS is a selective oxidant that can oxidize alcohols to aldehydes or ketones, especially in the oxidation reaction of alcohols and ethers, showing excellent selectivity and efficiency. It can provide precise chemical transformation when synthesizing compounds containing ketones or aldehydes.
2. Free radical initiator
NBS promotes polymerization reactions by generating stable free radicals. It is often used as an initiator for free radical polymerization reactions in polymer synthesis and polymerization chemistry, especially in the manufacture of polymer materials and the synthesis of new polymers.
3. Bromination reaction
NBS is a commonly used bromination reagent, mainly used for selective bromination reactions, especially in the allylic bromination of olefins and the side chain bromination of aromatic compounds. Compared with other bromination agents, NBS can provide higher selectivity and milder reaction conditions.
4. Pharmaceutical Chemistry and Natural Product Synthesis
BS is used to introduce bromine atoms or perform oxidation reactions to synthesize biologically active compounds. It is used not only as a bromination reagent, but also as an oxidant in drug synthesis to achieve the desired chemical transformation, thereby helping to synthesize pharmacologically active molecules.
5. Synthetic intermediates
NBS is a key intermediate for the synthesis of pesticides, dyes and additives. Its high efficiency helps to achieve precise chemical transformations of complex organic molecules.
6. Laboratory Applications
NBS is used in laboratory research to explore new reaction pathways and synthetic methods. With its high efficiency and selectivity, it has become an important tool for chemists to develop new reactions.
Storage conditions: Ventilate and dry at low temperature, separate from aniline, dialkyl sulfide, hydrazine hydrate, peroxide and propionitrile.
Packing: This product is packed in 25kg cardboard drums, and it can also be customized according to customers' requirements