Guanidine Thiocyanate CAS 593-84-0
Chemical name: Guanidine Thiocyanate
Synonymous names: Guanidine isothiocyanate;
CAS No: 593-84-0
EINECS No: 209-812-1
Molecular formula: CH5N3CHNS
Content: ≥99.5%
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Structural formula:
Product Description:
Index |
Specification |
Results |
APPEARANCE |
White to off-white crystalline powder |
Complies |
ASSAY≥% |
99.5 |
99.67 |
AMMONIUM≤% |
0.1 |
0.02 |
ASH≤% |
0.1 |
0.07 |
WATER CONTENT≤% |
0.3 |
0.25 |
Melting point℃ |
118-121 |
118.4-120.1 |
PH (11.8%IN WATER) |
5-7 |
6.22 |
UV-ABSORBNNCE A(280nm) 35%1N WATER |
<0.4 |
0.211 |
UV-ABSORBNNCE A(300nm) 35%1N WATER |
<0.05 |
0.026 |
Fe |
<1ppm |
Complies |
Application areas:
1. Denaturation and lysis of cells: As a chaotropic agent and strong denaturant, guanidinium thiocyanate can effectively decompose cell structures and is an important part of the biological sample preparation process.
2. RNA and DNA extraction: Occupying a core position in RNA isolation technology, guanidine thiocyanate can inhibit the activity of nuclease and ensure the integrity and purity of nucleic acids.
3. Biological sample preservation: It is also widely used in the storage buffer of whole blood samples to ensure that the samples maintain their original state before analysis. It is especially suitable for the preservation and freezing of stool samples in DNA research.
4. Chemical synergy of RNA extraction: In the process of RNA extraction by phenol-chloroform method, the synergistic effect of guanidinium thiocyanate, b-mercaptoethanol and sodium lauryl sarcosinate not only denatures the protein to release RNA, but also It also maintains the stability of DNA under acidic conditions, ensuring the efficiency and accuracy of RNA extraction.
Packaging specifications:
25kg/barrel, or 25kgs per carton ;packaging can also be customized according to customer requirements.
Storage conditions:
Need to be sealed and stored in a cool, dry place.
To obtain Guanidine Thiocyanate COA, TDS, and MSDS, please contact [email protected]