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Organic intermediate

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Chlorhexidine CAS 55-56-1

Chemical name: Chlorhexidine

Synonymous names:chlorhexidin;fimeil;hexadol

CAS No:55-56-1

Molecular formula:C22H30Cl2N10

Molecular weight:505.45

EINECS No:200-238-7

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Structural formula 

Product Description

Items

Specifications

Appearance

White Powder

Assay,%

99.0MIN

Loss On Drying

NMT 1.0 %

Residue On Ignition

NMT 0.1%

p-Chloroaniline

NMT 500ppm

 

Properties and Usage:

Chlorhexidine is a cationic surfactant with broad-spectrum antimicrobial effect, which mainly achieves bacteriostatic and bactericidal effects by disrupting bacterial cell membranes and causing cell contents to leak out. It has a significant inhibitory effect on both Gram-positive and negative bacteria, and has important applications in medical and sanitary disinfection.

 

Core application areas

Oral Care

Chlorhexidine is often used in oral rinses, due to its good broad-spectrum antimicrobial effect, it can effectively inhibit and kill bacteria in the oral cavity. Its molecules are positively charged and can adsorb with negatively charged plaques and mucosal surfaces in the oral cavity and gradually release the drug to form a continuous antibacterial effect for up to 24 hours. It is widely used in the treatment of gingivitis, oral infections and the prevention of oral infections in cancer and leukemia patients.

 

Pre-surgical and intra-operative sterilization

Chlorhexidine is one of the commonly used pre-surgical disinfectant drugs, applied to the disinfection of skin at the surgical site of doctors and patients, the disinfection of surgical instruments, and the disinfection of the ward environment. It maintains strong bactericidal effect under serum or blood interference and effectively prevents infection during surgery.

 

Wound care

Chlorhexidine is used to rinse and disinfect wounds, burns and impetigo. It achieves bactericidal effect by destroying bacterial cell membrane, and shows bacteriostatic effect at low concentration, while it has strong bactericidal efficacy at high concentration.

 

Skin and instrument disinfection

Chlorhexidine is widely used for disinfection of skin and medical devices, with strong antibacterial function, which can effectively prevent the spread of pathogenic bacteria. It is also commonly used in the treatment of skin problems such as eczema, dermatitis and burns. In addition, as an antiseptic, it can be used in eye drops to maintain eye hygiene.

 

Antimicrobial Formulation

In the pharmaceutical industry, chlorhexidine is often formulated into salts with other substances such as chlorhexidine hydrochloride, chlorhexidine acetate and chlorhexidine gluconate. These salt compounds have a wide range of applications in different pharmaceutical dosage forms, especially Chlorhexidine Gluconate, which has gradually become the main clinical choice in recent years.

 

Storage conditions: This product should be stored in an airtight container filled with argon.

Packing: This product is packed in 25kg cardboard drums, and it can also be customized according to customers' requirements

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