Structural formula:

【Chemical properties s】

White crystals are obtained from ether, with a melting point of 102~104 °C. Acute toxicity LD50 mice (mg/kg): >400 oral.

【Functions and Applications】

CAS 81409-90-7, an ergot alkaloid derivative, acts as a dopamine receptor agonist and acts similarly to bromocriptine. It is characterized by potency, long-acting and selectivity, with a high affinity for the D2 dopamine receptor. And it has a strong and long-lasting effect of inhibiting the secretion of mammary glands.

This product is easy to absorb, the peak time of plasma concentration is 1~3 hours, the plasma protein binding rate is 40%, and the half-life is 63~100 hours. This product is widely metabolized by hydrolysis and is mainly excreted through bile and feces.

It is mainly used for Parkinson's disease, Parkinsonism syndrome, and hyperprolactinemia. This product can reduce the severity of the "on-off phenomenon" caused by long-term use of levodopa, significantly increase the time in the "on" state, and reduce the demand for levodopa by 18%.

Long-acting dopamine antagonists. It is used to treat hyperprolactin caused by primary or pituitary tumors

【Packaging & Storage】

Bottle or foil bag or customized according to customer's requirements.

The product is hygroscopic, sealed and stored in a cool, dry place, away from fire, heat, strong oxidants and strong reducing agents.