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Overview of the Synthesis and Application of 2,5-Dimethoxy-β-Nitrostyrene

Aug 16, 2024 0

2,5-Dimethoxy-β-nitrostyrene (CAS 40276-11-7)

is a significant organic compound with wide-ranging applications in the pharmaceutical and organic synthesis industries.

This article delves into its chemical properties, synthesis methods, and diverse applications.

2,5-二甲氧基-β-硝基苯乙烯

Chemical Properties

        2,5-Dimethoxy-β-nitrostyrene has the molecular formula C10H11NO4 and a molecular weight of 209.2.

        It appears as an orange crystalline powder with a melting point between 116-120°C.

       These structural characteristics confer unique chemical properties, making it a vital compound in both organic synthesis and pharmaceutical research and development.

Synthesis Method

2,5-Dimethoxy-β-nitrostyrene is produced by the reaction of nitromethane and 2,5-dimethoxybenzaldehyde

2,5-二甲氧基-β-硝基苯乙烯合成式

Application Field 

  • Medical Field

2,5-dimethoxy-β-nitrostyrene serves as a crucial intermediate in organic synthesis, particularly in the development of antiviral and anticancer drugs.

Notably, it is used in the synthesis of tyrosine kinase inhibitors, which play a significant role in cancer treatment.

  • Organic Synthesis

In organic chemistry, this compound is utilized for synthesizing various nitrogen-containing active molecules.

Its unique properties make it an essential intermediate in numerous important chemical reactions.

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Conclusion

2,5-Dimethoxy-β-nitrostyrene's role in medicine and organic synthesis underscores its importance and potential.

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