(R)-(-)-Mandelic Acid CAS 611-71-2

Chemical Name: (R)-(-)-Mandelic Acid

Synonymous Names: D-Mandelic Acid; D-(-)-Mandelic Acid; (R)-α-Hydroxyphenylacetic Acid; (R)-(-)-Amygdalic Acid; (2R)-2-Hydroxy-2-phenylacetic Acid

CAS No.: 611-71-2

Molecular Formula: C₈H₈O₃

Molecular Weight: 152.15 g/mol

EINECS No.: 210-276-6

Inquiry

Description
Inquiry

(R)-(-)-Mandelic Acid is a white to light yellow crystalline powder. It is the R-enantiomer of mandelic acid and is mainly used as a chiral resolving agent and chiral building block in organic and pharmaceutical synthesis. Its defined R configuration makes it useful when control of molecular chirality is required.

Structural formula:

Product Specification

Item	Specification
Product Name	(R)-(-)-Mandelic Acid
CAS Number	611-71-2
Appearance	White to light yellow crystals or crystalline powder
Assay	≥98.5%
Optical Purity	≥98.5% ee
Melting Point	131–133°C
Specific Optical Rotation	−157° to −153°
Molecular Weight	152.15 g/mol

(R)-(-)-Mandelic Acid Applications

Chiral Resolution: (R)-(-)-Mandelic Acid is widely used as a chiral resolving agent. It can react with a racemic amine or other suitable chiral compound to form a pair of diastereomeric salts.

Pharmaceutical Synthesis: (R)-(-)-Mandelic Acid is used as a chiral building block in pharmaceutical synthesis. Commercial chemical references specifically describe its use in the preparation of semisynthetic cephalosporins and penicillins.

Chiral Organic Synthesis: The defined R configuration of (R)-(-)-Mandelic Acid makes it useful in asymmetric and chiral synthesis. It can be used as a chiral acid or building block when the stereochemical structure of the target compound needs to be controlled.