(3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone CAS 149249-91-2

Chemical Name: (3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone

Synonymous Names: (+)-cis-1-Benzoyl-3-triethylsilyloxy-4-phenyl-2-azetidinone; (3R,4S)-1-Benzoyl-3-[(triethylsilyl)oxy]-4-phenyl-2-azetidinone; Paclitaxel Side Chain No. 2

CAS No.: 149249-91-2

Molecular Formula: C₂₂H₂₇NO₃Si

Molecular Weight: 381.54 g/mol

EINECS No.: Not listed

(3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone is typically supplied as a colorless to pale yellow oil. It is a chiral β-lactam intermediate featuring a specific protecting group structure, designed for subsequent chemical transformations.

Structural formula: (3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone CAS 149249-91-2

Product Specification

ItemSpecification
Product Name(3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone
CAS Number149249-91-2
Molecular FormulaC22H27NO3Si
Molecular Weight381.54 g/mol
AppearanceColorless to pale yellow oil; some grades may be supplied as white powder
Purity≥95.0%
Water≤1.0%

(3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone Applications

1.Pharmaceutical Intermediate

Its primary use is as a pharmaceutical intermediate in the synthesis of taxane compounds.

2.Synthesis of Paclitaxel and Related Taxanes

This compound serves as a protected chiral building block in the synthesis of paclitaxel and other taxane compounds.

Packaging & Storage

Packaging: Available packaging options include 1 kg packs and 25 kg drums.

Storage: Store in a sealed container in a cool, dry place.

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