(3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone CAS 149249-91-2
Chemical Name: (3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone
Synonymous Names: (+)-cis-1-Benzoyl-3-triethylsilyloxy-4-phenyl-2-azetidinone; (3R,4S)-1-Benzoyl-3-[(triethylsilyl)oxy]-4-phenyl-2-azetidinone; Paclitaxel Side Chain No. 2
CAS No.: 149249-91-2
Molecular Formula: C₂₂H₂₇NO₃Si
Molecular Weight: 381.54 g/mol
EINECS No.: Not listed
(3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone is typically supplied as a colorless to pale yellow oil. It is a chiral β-lactam intermediate featuring a specific protecting group structure, designed for subsequent chemical transformations.
Structural formula: ![(3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone CAS 149249-91-2](https://fscichem.com/wp-content/uploads/2026/09/3R4S-1-Benzoyl-4-phenyl-3-triethylsilyloxy-2-azetidinone-CAS-149249-91-2.jpg)
Product Specification
| Item | Specification |
| Product Name | (3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone |
| CAS Number | 149249-91-2 |
| Molecular Formula | C22H27NO3Si |
| Molecular Weight | 381.54 g/mol |
| Appearance | Colorless to pale yellow oil; some grades may be supplied as white powder |
| Purity | ≥95.0% |
| Water | ≤1.0% |
(3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone Applications
1.Pharmaceutical Intermediate
Its primary use is as a pharmaceutical intermediate in the synthesis of taxane compounds.
2.Synthesis of Paclitaxel and Related Taxanes
This compound serves as a protected chiral building block in the synthesis of paclitaxel and other taxane compounds.
Packaging & Storage
Packaging: Available packaging options include 1 kg packs and 25 kg drums.
Storage: Store in a sealed container in a cool, dry place.

![(3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone CAS 149249-91-2 Supply (3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone CAS 149249-91-2 Supply](https://fscichem.com/wp-content/uploads/2026/09/3R4S-1-Benzoyl-4-phenyl-3-triethylsilyloxy-2-azetidinone-CAS-149249-91-2-Supply.jpg)





